GHK-Cu
A naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. Studied extensively for collagen synthesis and gene expression modulation.
300 in stock
For laboratory and in vitro research purposes only. Not for human consumption.
What is GHK-Cu?
GHK-Cu is a naturally occurring copper-binding tripeptide — just three amino acids — found in human plasma, saliva, and urine. Despite its small size, it has one of the most studied molecular profiles in peptide research. A landmark genomic study found it modulates expression of over 4,000 human genes. Researchers have focused on its role in collagen and elastin synthesis, wound healing, and suppression of inflammatory mediators like TNF-α and IL-6. It is one of the few peptides that occurs naturally in the body and has a well-characterized mechanism backed by decades of published science.
three amino acids.
four thousand genes.
GHK-Cu is a copper-binding tripeptide found naturally in human plasma. A landmark genomic study documented it influencing the expression of over 4,000 human genes — including pathways tied to collagen production, inflammation control, and tissue remodeling. Small molecule. Large research footprint.
How GHK-Cu works in research models
GHK-Cu is a tripeptide–copper complex that activates multiple wound-healing pathways simultaneously. Research shows it upregulates collagen, elastin, and VEGF expression while suppressing inflammatory mediators including TNF-α and IL-6. A landmark genomic study found GHK-Cu modulates expression of over 4,000 human genes — including pathways involved in tissue remodeling, anti-oxidation, and anti-inflammatory signaling.
independently tested.
≥99.4% purity. every lot.
Rowan GHK-Cu is verified at ≥99.4% HPLC purity by Janoshik Analytical. Mass spec confirmed. Your Certificate of Analysis is tied to the specific lot on your vial — not a generic batch report.
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.
Int J Mol Sci · 2018 · PMID: 29874866
Using Copper to Fight Microorganisms.
Curr Chem Biol · 2012
GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration.
Biomed Res Int · 2015 · PMID: 25883984
Research protocols typically use GHK-Cu at 1–2 mg/kg in in vivo models. For in vitro cell culture applications, concentrations from 1–100 nM are commonly reported. Reconstitute with sterile water. Store at 4°C after reconstitution and use within 30 days.
You ask, we answer.
The copper is chelated to the peptide as Cu²⁺ (cupric ion), which is the biologically active form studied in the literature.
Yes. GHK-Cu is typically used at nanomolar concentrations in cell culture, making 50mg a substantial research supply.
Yes. Copper peptides are photosensitive. Store away from direct light and use amber or opaque containers for reconstituted solutions.
GHK-Cu is primarily studied for its role in skin remodeling and wound healing. Research has documented upregulation of collagen, elastin, and VEGF expression, while also showing suppression of inflammatory mediators including TNF-α and IL-6.
Yes. GHK-Cu is the most well-known and studied copper peptide, sometimes referred to simply as "copper peptide" in the research and cosmetic literature. It consists of glycine, histidine, and lysine tripeptide bound to a Cu²⁺ ion.
GHK-Cu is used at much lower molar concentrations than many peptides — typically nanomolar ranges in cell culture. Because of this, 50mg is a standard and practical research quantity, providing a substantial supply for multiple experimental runs.
Research Use Only
All Rowan Peptides products are intended strictly for laboratory and in vitro research purposes. They are not approved by the FDA and are not intended for human consumption, veterinary use, or any therapeutic application. By purchasing, you agree to our Terms of Service and Indemnity Waiver. Rowan Peptides LLC operates as a chemical supplier only.
Three orders in now. The consistency between batches is what keeps me coming back. Lot numbers match the published COAs every time. That's the whole game.
Was comparing Rowan against two other vendors. The third party testing and the fact that the site explains the compound without overclaiming made me choose Rowan. Good call. Reordered already.
I research skin peptides professionally and GHK-Cu is one I've ordered from multiple suppliers over the years. Rowan's is the cleanest I've seen from a consumer-facing brand. 50mg, lab grade, COA matches what I'd expect. Found this brand through someone at a conference and it lives up to the word of mouth.
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